Zyprexa Reviewed for Children's Use

Zyprexa has come up a lot on this blog lately. It's come up again - an FDA Panel has been formed to review Zyprexa off-label use for children. Apparently Zyprexa is supposed to be prescribed for schizophrenia and bipolar disorder, but is often prescribed for off-label disorders such as dementia and mild bipolar disorder. Another off-label prescription has been for kids. The FDA Panel has been convened to see about adding side effect warnings specifically for kids - as Zyprexa has been known to cause diabetes and other blood-sugar disorders.

Eli-Lilly is apparently pushing the FDA to approve Zyprexa for children between 13-17. With the not-uncommon side effect of diabetes, I wouldn't want my kid on it.

Zyprexa News

A Brooklyn judge decided to unseal the previously confidential court documents regarding Zyprexa. They can be downloaded from here.

Great Links About Psychiatry

Here's some great links I found this week:

Scientology Lives reports connections between school shooters and psychiatric drugs

DBunker reports that the FDA is cracking down on neighborhood pharmacies

Alliance for Human Research Project reports about Eli Lilly concealing information

Pharmalot reports that Eli Lilly should have warned the American people about Zyprexa back in 1998

Grahame reports about a new anti-depressant (called Placebozac) that has just come on the market *This one deserves a warning for excessive sarcasm*

Attention Deficit Disorder reports some interesting statistics about ADHD kids

PsychWatch reports 8 reasons to run from Anti-Depressants

The FDA - A Step in the Right Direction

While it seems that anything the FDA does is based upon an imperfect system, there is a new effort being launched by the FDA to oversee the side-effects of prescription drugs. I believe (but this is unverified) that they might be making a data base of these side-effects available for consumer use, which would be incredibly beneficial.

So, pros:
a) A database with side-effect listed (yay!) so we don't all have to read ten pages of fine print when a drug is prescribed to us.
b) More oversite on prescription drugs so that things like the Zyprexa debacle aren't repeated.

Cons:
a) In usual FDA fashion, the new effort (called "Safety First") might be unwilling to pull a drug they have already approved.
b) They could get in cahoots with various drug manufacturers.

I say that this is a change for the better. The Pros are something new and the Cons are cons that have been around since the FDA's inception. What do you think?

Woops - Lawyer Spills the Beans on Secret Eli Lilly Court Case

I read this news article and had to laugh. It seems that Eli Lilly was marketing a drug called Zyprexa improperly. Zyprexa has serious side effects, such as diabetes, hypoglycemia and more and is only approved to treat people with schizophrenia and severe bipolar disorder (like they need diabetes on top of all that?). Some documents from Eli Lilly revealed that they were pushing doctors to prescribe the drug for other disorders like age related dementia and mild bi-polar. Because of this, Eli Lilly will have to pay federal and state governments more than 1 billion dollars. This fine is in addition to the 1.2 billion dollars Eli Lilly has already paid in lawsuits from people who say they developed diabetes because of Zyprexa (which apparently is not a rare side effect of Zyprexa).
All this information and more was leaked to the New York Times in an email screw up by one of Eli Lilly's lawyers. He was trying to send an internal document to another lawyer, but ended up sending it to a press agent with the same last name. Woops!